Embarking on a cruise to South America is a captivating voyage that promises a seamless blend of luxury and exploration. These cruises allow travelers to navigate the continent's diverse coastal wonders, offering a unique perspective on its iconic landmarks and hidden gems. Whether sailing along the Brazilian coast with its lively beach cities, exploring the fjords of Chile and Argentina, or navigating the historic waters around the Galápagos Islands, each itinerary is carefully curated to showcase the best of South America. Onboard amenities and curated shore excursions provide passengers with opportunities to immerse themselves in local cultures, savor exotic cuisines, and witness the natural beauty that defines this extraordinary part of the world. With the comfort of a floating sanctuary and the thrill of discovering new landscapes each day, a cruise to South America is a voyage that promises to create indelible memories for every traveler.
South America Itineraries (Page 3)
12 Nights
Chilean Fjords & Scenic Shores
Chilean Fjords & Scenic Shores
Departure Date
30 Oct 25
| Cruise Line | Viking Ocean Cruises |
| Cruise Type | |
| Ship | Viking Octantis |
| Region | South America |
| Departure Port | Valparaiso |
| Destination Port | Ushuaia |
| Itinerary | Valparaiso, Puerto Chacabuco, Chilean Fjords, Chilean Fjords, Punta Arenas, Chilean Fjords, Garibaldi Fjord, Alberto de Agostini National Park and Ushuaia |
From £7,995pp
Plus substantial savings from Deluxe Cruises
14 Nights
San Cristóbal, Galapagos to San Cristóbal, Galapagos
San Cristóbal, Galapagos to San Cristóbal, Galapagos
Departure Date
01 Nov 25
| Cruise Line | Silversea |
| Cruise Type | Ocean |
| Ship | Silver Origin |
| Region | South America |
| Departure Port | San Cristóbal Island, Galápagos |
| Destination Port | San Cristóbal Island, Galápagos |
| Itinerary |
From £18,200pp
Plus substantial savings from Deluxe Cruises
11 Nights
Expedition Central America With Panama Canal - The Beauty Of The Panama Canal
Expedition Central America With Panama Canal - The Beauty Of The Panama Canal
Departure Date
08 Nov 25
| Cruise Line | Hapag-Lloyd Cruises |
| Cruise Type | Ocean |
| Ship | Hanseatic Inspiration |
| Region | South America |
| Departure Port | Panama City |
| Destination Port | Colón |
| Itinerary | Panama City, Quepos (Puerto Quepos), Isla Iguana, Colón and Colón |
From £5,667pp
Plus substantial savings from Deluxe Cruises
25 Nights
Call Of The Amazon
Call Of The Amazon
Departure Date
12 Nov 25
| Cruise Line | Oceania Cruises |
| Cruise Type | Ocean |
| Ship | Insignia |
| Region | South America |
| Departure Port | Miami, Florida |
| Destination Port | Miami, Florida |
| Itinerary | Miami, Florida, Saint John's, Castries, Saint George's, Scarborough, Santarém, Boca de Valeria, Manaus, Manaus, Parintins, Alter do Chão, Bridgetown, Roseau, Philipsburg, San Juan (Puerto Rico) and Miami, Florida |
From £5,369pp
Plus substantial savings from Deluxe Cruises
16 Nights
Expedition South America With Panama Canal - Mysterious Equatorial Adventure
Expedition South America With Panama Canal - Mysterious Equatorial Adventure
Departure Date
19 Nov 25
| Cruise Line | Hapag-Lloyd Cruises |
| Cruise Type | Ocean |
| Ship | Hanseatic Inspiration |
| Region | West Coast US, South America and Panama Canal |
| Departure Port | Colón |
| Destination Port | Valparaiso |
| Itinerary | Colón, San Miguel Bay, Punta Alegre, Utría National Park, Isla de la Plata, Salaverry, Callao, Paracas, Isla Pan de Azúcar and Valparaiso |
From £8,247pp
Plus substantial savings from Deluxe Cruises
17 Nights
South America & the Chilean Fjords
South America & the Chilean Fjords
Departure Date
29 Nov 25
| Cruise Line | Viking Ocean Cruises |
| Cruise Type | Ocean |
| Ship | Viking Jupiter |
| Region | South America |
| Departure Port | Buenos Aires |
| Destination Port | Valparaiso |
| Itinerary | Buenos Aires, Buenos Aires, Montevideo, Puerto Madryn, Port Stanley, Ushuaia, Punta Arenas, Puerto Montt, Valparaiso and Valparaiso |
From £6,790pp
Plus substantial savings from Deluxe Cruises
14 Nights
San Cristóbal, Galapagos to San Cristóbal, Galapagos
San Cristóbal, Galapagos to San Cristóbal, Galapagos
Departure Date
29 Nov 25
| Cruise Line | Silversea |
| Cruise Type | Ocean |
| Ship | Silver Origin |
| Region | South America |
| Departure Port | San Cristóbal Island, Galápagos |
| Destination Port | San Cristóbal Island, Galápagos |
| Itinerary | San Cristóbal Island, Galápagos, Roca León Dormido, Bartolome Island, Santiago Island, Galápagos, Punta Vicente Roca, Isabela Island, Galápagos, Punta Espinoza, Fernandina Island, Galápagos, Caleta Tagus, Elizabeth Bay, Isabela Island, Galápagos, Post Office Bay, Floreana, Galápagos, Champion Island, Galápagos, Punta Cormorant, Floreana Island, Galápagos, Puerto Ayora, Isla Santa Cruz, Los Gemelos, Santa Cruz Island, Galápagos, Dragon Hill, Santa Cruz Island, Galápagos, Isla Guy Fawkes, Galapagos, Santa Cruz Island, Galápagos, San Cristóbal Island, Galápagos, Roca León Dormido, San Cristóbal Island, Galápagos, El Barranco, Genovesa Island, Galápagos, Darwin Bay, Genovesa Island, Galápagos, North Seymour Island, Galapagos, Sullivan Bay, Santiago Island, Galápagos, Mangle Point, Fernandina Island, Galápagos, Punta Moreno, Isabella Island, Galapagos, Los Gemelos, Santa Cruz Island, Galápagos, Puerto Ayora, Isla Santa Cruz, Gardner Bay, Española Island, Galápagos, Punta Suarez, Isla Española, Galápagos, San Cristóbal Island, Galápagos, Cerro Brujo, San Cristóbal Island, Galápagos and San Cristóbal Island, Galápagos |
From £18,400pp
Plus substantial savings from Deluxe Cruises
22 Nights
Palms To Andean Peaks
Palms To Andean Peaks
Departure Date
29 Nov 25
| Cruise Line | Oceania Cruises |
| Cruise Type | Ocean |
| Ship | Marina |
| Region | South America |
| Departure Port | Miami, Florida |
| Destination Port | San Antonio |
| Itinerary | Miami, Florida, Cozumel, Costa Maya, Belize City, Harvest Caye, Santo Tomás de Castilla, Roatán Island, Puerto Limón, Panama City, Panama City, Manta, Guayaquil, Salaverry, Callao, Coquimbo, San Antonio and San Antonio |
From £4,487pp
Plus substantial savings from Deluxe Cruises
42 Nights
Iconic Isles To Icebergs
Iconic Isles To Icebergs
Departure Date
29 Nov 25
| Cruise Line | Oceania Cruises |
| Cruise Type | Ocean |
| Ship | Marina |
| Region | South America |
| Departure Port | Miami, Florida |
| Destination Port | Buenos Aires |
| Itinerary | Miami, Florida, Cozumel, Costa Maya, Belize City, Harvest Caye, Santo Tomás de Castilla, Roatán Island, Puerto Limón, Panama City, Panama City, Manta, Guayaquil, Salaverry, Callao, Coquimbo, San Antonio, San Antonio, Puerto Montt, Castro, Puerto Chacabuco, Laguna San Rafael National Park, Punta Arenas, Ushuaia, Port Stanley, Puerto Madryn and Buenos Aires |
From £8,969pp
Plus substantial savings from Deluxe Cruises
20 Nights
Highlights of Antarctica, Argentina and Brazil - Cruise & Land Journey
Highlights of Antarctica, Argentina and Brazil - Cruise & Land Journey
Departure Date
02 Dec 25
| Cruise Line | Scenic Ocean Cruises |
| Cruise Type | Ocean |
| Ship | Scenic Eclipse |
| Region | South America |
| Departure Port | Rio de Janeiro |
| Destination Port | Ushuaia |
| Itinerary | Rio de Janeiro, Rio de Janeiro, Rio de Janeiro, Rio de Janeiro, Iguazú Falls, Iguazú Falls, Iguazú Falls, Iguazú Falls, Buenos Aires, Buenos Aires, Buenos Aires, Buenos Aires, Ushuaia, Antarctic Peninsula, Antarctic Peninsula, Antarctic Peninsula, Antarctic Peninsula, Antarctic Peninsula, Antarctic Peninsula, Ushuaia, Ushuaia and Buenos Aires |
From £20,568pp
Plus substantial savings from Deluxe Cruises
14 Nights
Season Of Samba
Season Of Samba
Departure Date
03 Dec 25
| Cruise Line | Regent Seven Seas Cruises |
| Cruise Type | Ocean |
| Ship | Seven Seas Splendor |
| Region | South America |
| Departure Port | Bridgetown |
| Destination Port | Rio de Janeiro |
| Itinerary | Bridgetown, Kingstown, Scarborough, Devil's Island, Fortaleza, Recife, Maceió, Salvador de Bahia, Rio de Janeiro and Rio de Janeiro |
From £7,169pp
Plus substantial savings from Deluxe Cruises
15 Nights
Expedition Chilean Fjords - Humankind Dwarfed By The Scale Of Nature
Expedition Chilean Fjords - Humankind Dwarfed By The Scale Of Nature
Departure Date
05 Dec 25
| Cruise Line | Hapag-Lloyd Cruises |
| Cruise Type | Ocean |
| Ship | Hanseatic Inspiration |
| Region | South America |
| Departure Port | Valparaiso |
| Destination Port | Ushuaia |
| Itinerary | Valparaiso, Puerto Montt, Puerto Natales, Punta Arenas, Garibaldi Glacier and Ushuaia |
From £8,591pp
Plus substantial savings from Deluxe Cruises